*業績 [#x874c684]
**学術論文 [#ne5ba288]
  &color(darkgreen){2014年};
-Nunomura W, Isozumi N, Nakamura S, Jinbo Y, Sasakura D, Ohki S, Kidokoro S, Wakui H, Takakuwa Y, "Unique structural changes in calcium-bound calmodulin upon interaction with protein 4.1R FERM domain: novel insights into the calcium-dependent regulation of 4.1R FERM domain binding to membrane proteins by calmodulin", [[Cell Biochemistry and Biophysics, ''69'', 7-19 (2014):http://www.ncbi.nlm.nih.gov/pubmed/24081810]]~

-城所俊一,“タンパク質の熱力学的安定性と分子機能の精密熱量測定” 熱測定, (学会賞受賞講演), "41", 2-9 (2014)

  &color(darkgreen){2013年};
-Nunomura W, Isozumi N, Nakamura S, Jinbo Y, Sasakura D, Ohki S, Kidokoro S, Wakui H, Takakuwa Y, "Unique structural changes in calcium-bound calmodulin upon interaction with protein 4.1R FERM domain: novel insights into the calcium-dependent regulation of 4.1R FERM domain binding to membrane proteins by calmodulin", [[Cell Biochemistry and Biophysics, in press:http://www.ncbi.nlm.nih.gov/pubmed/24081810]]~

-Wakai S, Kidokoro S, Masaki K, Nakasone K, Sambongi Y, "Constant Enthalpy Change Value during Pyrophosphate Hydrolysis within the Physiological Limits of NaCL.", [[Journal of Biological Chemistry, ''288'', 29247-29251 (2013):http://www.ncbi.nlm.nih.gov/pubmed/23965994]]~

-Nakamura S, Koga S, Shibuya N, Seo K, Kidokoro S, "A New Multi-Binding Model for Isothermal Titration Calorimetry Analysis of the Interaction between Adenosine 5’-Triphosphate and Magnesium Ion", [[Thermochimica Acta, ''563'', 82-89 (2013):http://www.sciencedirect.com/science/journal/00406031/563]]~



  &color(darkgreen){2012年};

-Nakamura S, Kidokoro S, "Volumetric properties of the molten globule state of cytochrome c on the thermal three-state transition evaluated by pressure perturbation calorimetry", [[The Journal of Physical Chemistry B, ''116'', 1927-1932 (2012):http://www.ncbi.nlm.nih.gov/pubmed/22201547]]~

  &color(darkgreen){2011年};

-Nunomura W, Sasakura D, Shiba K, Nakamura S, Kidokoro SI, Takakuwa Y, "Structural stabilization of protein 4.1R FERM domain upon binding to apo-calmodulin: Novel insights into the biological significance of the calcium-independent binding of calmodulin to protein 4.1R", [[Biochemical Journal, ''440'', 367-374 (2011):http://www.ncbi.nlm.nih.gov/pubmed/21848512/]]

-Noguchi S, Takemoto S, Kidokoro S, Yamamoto K, Hashimoto M, "Syntheses of cellotriose and cellotetraose analogues as transition state mimics for mechanistic studies of cellulases",  [[Bioorganic & Medicinal Chemistry, ''19'', 3812-3830 (2011):http://www.ncbi.nlm.nih.gov/pubmed/21602048/]]

-Nakamura S, Seki Y, Katoh E, Kidokoro S, "Thermodynamic and structural properties of the acid molten globule state of horse cytochrome c", [[Biochemistry, ''50'', 3116-3126 (2011):http://www.ncbi.nlm.nih.gov/pubmed/21388230/]]

-Xiang H, Takeuchi H, Tsunoda Y, Nakajima M, Murata K, Ueguchi-Tanaka M,
Kidokoro S, Kezuka Y, Nonaka T, Matsuoka M, Katoh E., "Thermodynamic
characterization of OsGID1-gibberellin binding using calorimetry and docking
simulations",  [[Journal of Molecular Recognition, ''24'', 275-282 (2011):http://www.ncbi.nlm.nih.gov/pubmed/21360613/]]

  &color(darkgreen){2009年};

-Islam MM, Sohya S, Noguchi K, Kidokoro S, Yohda M, Kuroda Y. "Thermodynamic and
structural analysis of highly stabilized BPTIs by single and double mutations, [[Proteins, ''77'', 962-970 (2009):http://www.ncbi.nlm.nih.gov/pubmed/19830687/]]

-Sugino C, Hirose M, Tohda H, Yoshinari Y, Abe T, Giga-Hama Y, Iizuka R, Shimizu M, Kidokoro S, Ishii N, Yohda M, "Characterization of a sHsp of Schizosaccharomyces pombe, SpHsp15.8, and the implication of its functional mechanism by comparison with another sHsp, SpHsp16.0.", [[Proteins, ''74'', 6-17 (2009):http://www.ncbi.nlm.nih.gov/pubmed/18543332/]]

  &color(darkgreen){2008年};

-清水由隆, 小棹理子, 川路均, 城所俊一, 木村隆良, 古賀信吉, 澤田豊, 西本右子, 
山崎淳司, 吉田博久, 加藤英司,“示差走査熱量計校正用標準物質としてのシクロヘキサンの妥当性に関するラウンドロビンテスト” 熱測定, 35, 68-75, (2008) 

-Kazunori Yamamoto, Yu Sato, Ayumi Ishimori, Kazuo Miyairi, Toshikatsu Okuno, 
Nobuaki Nemoto, Hiroki Shimizu, Shun-ichi Kidokoro, Masaru Hashimoto "Synthesis of D-trigalacturonic acid methylglycoside and conformational comparison with its sulfur analogue" [[Biosci.Biotech.Biochem, ''72'', 2039-2048 (2008):http://www.ncbi.nlm.nih.gov/pubmed/18685224/]]

-Itagaki T, Nishizaki S, Sekihashi K, Kobayashi H, Kidokoro S, Kezuka Y, Arata Y, Hirabayashi J, Kasai K, Nonaka T, "Crystallization and preliminary x-ray crystallographic analysis of galectin LEC-1 from Caenorhabditis elegans.", [[Protein & Peptide Letters, ''15'', 419-422 (2008):http://www.ncbi.nlm.nih.gov/pubmed/18473958/]]


-Sawano M, Yamamoto H, Ogasahara K, Kidokoro S, Katoh S, Ohnuma T, Katoh E, Yokoyama S, Yutani K, "Thermodynamic basis for the stabilities of three CutA1s from Pyrococcus horikoshii,Thermus thermophilus, and Oryza sativa, with unusually high denaturation temperatures.", [[Biochemistry, ''47'', 721-730 (2008):http://www.ncbi.nlm.nih.gov/pubmed/18154307/]]

-Saji H, Iizuka R, Yoshida T, Abe T, Kidokoro S, Ishii N, Yohda M, "CRole of the IXI/V motif in oligomer assembly and function of StHsp14.0, a small heat shock protein from the acidothermophilic archaeon, Sulfolobus tokodaii strain 7.", [[Proteins, ''71'', 771-782 (2008):http://www.ncbi.nlm.nih.gov/pubmed/17979194/]]

  &color(darkgreen){2007年};

-Kato A, Yamada M, Nakamura S, Kidokoro S, Kuroda Y, "Thermodynamic properties of BPTI variants with highly simplified amino acid sequences.", [[Journal of Molecular Biology, ''372'', 737-746 (2007):http://www.ncbi.nlm.nih.gov/pubmed/17686492/]]

-中村成芳, 城所俊一 "シトクロムcモルテングロビュール状態に関する熱力学的研究", [[熱測定(解説記事), ''34(No3)'', 113-119 (2007):http://www.netsu.org/j+/Jour_J/index.html]]←リンク先からPDF閲覧できます。

-Nakamura S, Baba T, Kidokoro S, "A molten globule-like intermediate state detected in the thermal transition of cytochrome c under low salt concentration.", [[Biophysical Chemistry, ''127'', 103-112 (2007):http://www.ncbi.nlm.nih.gov/pubmed/17257735/]]

  &color(darkgreen){2006年};

-Karim N, Kidokoro S, "Precise evaluation of enzyme activity using isothermal titration calorimetry", [[熱測定(解説記事), ''33(No1)'', 27-35 (2006):http://www.netsu.org/j+/Jour_J/index.html]]←リンク先からPDF閲覧できます。

  &color(darkgreen){2005年};

-Nakamura S, Kidokoro S, "Direct observation of the enthalpy change accompanying the native to molten-globule transition of cytochrome c by using isothermal acid-titration calorimetry.", [[Biophysical Chemistry, ''113'', 161-168 (2005):http://www.ncbi.nlm.nih.gov/pubmed/15617823/]]

-Karim N, Okada H, Kidokoro S, "Calorimetric evaluation of the activity and the mechanism of cellulase for the hydrolysis of cello-oligosaccharides accompanied by the mutarotation reaction of the hydrolyzed products.", [[Thermochimica Acta, ''431'', 9-20 (2005):http://www.sciencedirect.com/science/article/pii/S0040603105000377/]]

  &color(darkgreen){2004年};

-Nakamura S, Kidokoro S, "Isothermal acid-titration calorimetry for evaluating the pH dependence of protein stability.", [[Biophysical Chemistry, ''109'', 229-249 (2004):http://www.ncbi.nlm.nih.gov/pubmed/15110942/]]

-Karim N, Kidokoro S, "Precise and continuous observation of cellulase-catalyzed hydrolysis of cello-oligosaccharides using isothermal titration calorimetry.", [[Thermochimica Acta, ''412'', 91-96 (2004):http://www.sciencedirect.com/science/article/pii/S0040603103004441/]]

  &color(darkgreen){2003年};

-Ali SA, Iwabuchi N, Matsui T, Hirota K, Kidokoro S, Arai M, Kuwajima K, Schuck P, Arisaka F, "Reversible and fast association equilibria of a molecular chaperone, gp57A, of bacteriophage T4.", [[Biophysical Journal, ''85'', 2606-2618 (2003):http://www.ncbi.nlm.nih.gov/pubmed/14507723/]]

  &color(darkgreen){2002年};

-城所俊一, "生体ナノマシンと材料設計" まてりあ, ''41'', 877-882 (2002)

  &color(darkgreen){2001年};

-Shun-ichi Kidokoro, "Calorimetric evaluation of protease activity" [[熱測定(解説記事), ''28(No2)'', 74-82 (2001):http://www.netsu.org/j+/Jour_J/index.html]]←リンク先からPDF閲覧できます。

-Takeo Usui, Sachiko Kojima, Shun-ichi Kidokoro, Kazunori Ueda, 
Hiroyuki Osada, Mikiko Sodeoka, "Design and synthesis of a dimeric derivative of  RK-682 with increased inhibitory activity against VHR, a dual-specificity ERK phosphatase: implications for the molecular mechanism of the inhibition" [[Chimistry & Biology, ''8'', 1209-1220 (2001):http://www.sciencedirect.com/science/article/pii/S1074552101000898]]

[[2000年以前の業績]]

**総説 [#n7446230]

-城所俊一, "精密熱量測定による糖加水分解酵素活性と触媒機構の解析" 酵素工学ニュース, 55, 11-17, (2006)

-城所俊一, “熱測定" 蛋白質核酸酵素, 49, 1720-1726, (2004)

[[2000年以前の業績]]

**書籍等 [#x4dcf28c]

-宇於崎麻衣子,城所俊一, 「等温滴定型熱量計を用いた分子間相互作用」, pp.144-150.
分子間相互作用解析ハンドブック, 磯部俊明ほか編, 羊土社, 2007年

-城所俊一, 「蛋白質の改変と熱力学的解析」, pp.488-490. 生物物理学ハンドブック, 石渡信一ほか編, 朝倉書店, 2007年

-城所俊一, 「タンパク質立体構造転移の熱量測定」, pp.197-210. タンパク質科学,後藤祐児他編,化学同人,2005年

-城所俊一, 「概説」, pp.285-287,「生体分子の安定性と熱測定」, pp.287-301. 第5版実験化学講座6 温度・熱,圧力, 日本化学会編,丸善,2005年

-城所俊一, 「生体物質」, pp.232-242. 最新 熱分析,小沢丈夫・吉田博久編,講談社,2005年

-S. Kidokoro, “Statistical mechanical analysis of protein heat capacity accompanied with thermal transition”, pp.333-341. The Nature of Biological Systems as Revealed by Thermal Methods, 
D. Lorinczy ed., Kluwer Acad. Pub., (2004)

-林・岩崎容子,城所俊一, 「熱測定による解析」, pp.138-150. ポストシークエンスタンパク質実験法〈3〉構造・機能解析の基礎, 大島泰郎他編, 東京化学同人, 2002年

-城所俊一, 「生体ナノマシンとは何か」, pp.1-14,「物理的摂動法による高機能化」, pp.38-69. 生体ナノマシンの分子設計, 城所俊一編, 共立出版, 2001年

[[2000年以前の業績]]


**特許 [#i7c90c2c]

-沼尾長徳,城所俊一
「生理活性ポリペプチド又はポリヌクレオチド中の作用部位の推定方法」
特開平05-130889  

-青山淳夫,米屋隆,甲斐建一,三宅俊男,城所俊一,三木洋一郎,
遠藤きみ子,和田昭允 
「新規プロテア-ゼ」
特開平05-146292  

-沼尾長徳,城所俊一 
「生理活性ポリペプチド中の作用部位の予測方法 」
特開平05-155899  

-米屋隆,青山淳夫,三宅俊男,長尾洋昌,城所俊一,三木洋一郎,
遠藤きみ子,和田昭允
「新規プロテア-ゼ」
特開平05-199872  

-米屋隆,青山淳夫,三宅俊男,長尾洋昌,城所俊一,三木洋一郎,
遠藤きみ子,和田昭允 
「新規プロテア-ゼ」
特開平05-199873  

-甲斐建一,長尾洋昌,三宅俊男,青山淳夫,米屋隆,城所俊一,
三木洋一郎,遠藤きみ子,和田昭允 
「新規プロテア-ゼ」
特開平06-046850

-米屋隆,青山淳夫,甲斐建一,長尾洋昌,三沢孝一,大江正剛,
半谷友美,家亀晴宇,城所俊一,三木洋一郎,遠藤きみ子,和田昭允
「新規プロテアーゼ」
特開平06-181761  

-田谷敏貴,保川清,城所俊一
「免疫化学測定法」
特開平09-218200 
 
-半澤敏,大江正剛,三宅俊男,城所俊一,遠藤きみ子,和田昭允
「新規なサーモライシン様プロテアーゼ及びその用途」
特開平09-220090

-保川清,城所俊一
「類似抗体の選別法及び抗体の立体構造の推測法」
特開平09-236601  

-田谷敏貴,保川清,城所俊一
「変異型抗体及びその作製法」
特開平09-241300  

-沼尾長徳,廣田裕己子,岩堀明代,城所俊一,伊東幸子,斉藤説子,
高尾賢一,加藤正,小林進
「1,1,6-トリ置換インダン誘導体並びに抗微生物剤及び脱炭酸触媒」
特開平11-222464  

-城所俊一
「分解反応測定用の物質およびそれを用いた測定法」
特開2000-187003

-田中良和,三宅俊男,半澤敏,大江正剛,城所俊一,三木洋一郎,
遠藤きみ子,和田昭允 
「バチルス由来の熱安定中性プロテアーゼの変異体 」
特表平11-501501

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